mHealth and Lifestyle Modifications

The mHealth and lifestyle modifications group investigates the impact of long-term habits  (e.g. dietary habits, physical activity) on psychological well-being and the brain. We use Ecological Momentary Assessment (EMA) methods to allow repeated sampling of subjects‘ current behaviours and experiences in real-time. A large array of neuroimaging methods (spectroscopic magnetic resonance imaging, quantitative MRI, fMRI, DTI) allows us to study the impact of lifestlye factors (e.g. physical activity) on brain metabolism, structure and function. Our primary goal is to gain a better understanding of the impact that lifestyle modifications can have on various psychological outcomes. Ultimately, we hope to develop optimal methods to complement pharmacological treatment of psychiatric conditions.

Our group is associated with the EU Eat2beNice Consortium

Group members:

Silke Matura (Group Leader)

Anne Siegl (Senior Scientist)

Alea Ruf (PhD student)

Hendrik Friedrichsen (MD student)

Hiba El Jomaa (MD student)

Annebirth Steinmann (MD student)

Söri Wenz (MD student)

Isabel Schnorr (MD student)

Mandy Raddatz (MD student)

Luise Wortmann (MSc student)

Krystyna Kotthaus (MSc student)

Lara Hamzhepour (MSc student)

Selected publications:

Engeroff, T., Fuzeki, E., Vogt, L., Fleckenstein, J., Schwarz, S., Matura, S., Pilatus, U., Deichmann, R., Hellweg, R., Pantel, J., & Banzer, W. (2018). Is Objectively Assessed Sedentary Behavior, Physical Activity and Cardiorespiratory Fitness Linked to Brain Plasticity Outcomes in Old Age? Neuroscience, 388, 384-392. doi:10.1016/j.neuroscience.2018.07.050

Oertel, V. & Matura, S. (Hrsg.) (2017). Bewegung und Sport gegen Burnout, Depressionen und Ängste. Heidelberg: Springer Verlag

Matura, S., Carvalho, A. F., Alves, G. S., & Pantel, J. (2016). Physical Exercise for the Treatment of Neuropsychiatric Disturbances in Alzheimer's Dementia: Possible Mechanisms, Current Evidence and Future Directions. Curr Alzheimer Res, 13(10), 1112-1123. Retrieved from

Matura, S., Fleckenstein, J., Deichmann, R., Engeroff, T., Fuzeki, E., Hattingen, E., Hellweg, R., Lienerth, B., Pilatus, U., Schwarz, S., Tesky, V. A., Vogt, L., Banzer, W., & Pantel, J. (2017). Effects of aerobic exercise on brain metabolism and grey matter volume in older adults: results of the randomised controlled SMART trial. Transl Psychiatry, 7(7), e1172. doi:10.1038/tp.2017.135

Matura, S., Prvulovic, D., Jurcoane, A., Hartmann, D., Miller, J., Scheibe, M., O'Dwyer, L., Oertel-Knochel, V., Knochel, C., Reinke, B., Karakaya, T., Fusser, F., & Pantel, J. (2014). Differential effects of the ApoE4 genotype on brain structure and function. Neuroimage, 89, 81-91. doi:10.1016/j.neuroimage.2013.11.042